Placental growth hormone in sheep : purification , properties and variations
نویسندگان
چکیده
The purification of a placental growth-promoting hormone, Ovine Chorionic Somatomammotropin (OCS), and its main physicochemical, immunological and biological properties were studied. OCS diffused into the amniotic fluid and was excreted into the allantoid fluid, but its concentrations in these compartments remained very low by comparison with the maternal or fetal serum. The total growth activity, as measured by radioreceptor assay in fetal serum, remained almost constant from day 60 to day 140 of pregnancy. Thus, fetal weight increase and total amounts of growth-promoting activities present (OCS + OGH) per fetus were about proportional.
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